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Founded on February 9, 1833 as Taladega, its name is changed to Macon on August 10, 1835 As of the censusGR2 of 2000, there were 2,461 people, 906 households, and 587 families residing in the city.

 The population density was 629.3/km? (1,624.8/mi?). There were 1,015 housing units at an average density of 259.5/km? (670.1/mi?). The racial makeup of the city was 31.49% White, 67.33% African American, 0.20% Native American, 0.41% Asian, 0.08% from other races, and 0.49% from two or more races. Hispanic or Latino of any race were 0.41% of the population.

There were 906 households out of which 32.6% had children under the age of 18 living with them, 34.0% were married couples living together, 27.5% had a female householder with no husband present, and 35.1% were non-families. 33.1% of all households were made up of individuals and 16.3% had someone living alone who was 65 years of age or older. The average household size was 2.53 and the average family size was 3.25.

In the city the population was spread out with 28.9% under the age of 18, 10.3% from 18 to 24, 27.8% from 25 to 44, 16.2% from 45 to 64, and 16.8% who were 65 years of age or older. The median age was 33 years. For every 100 females there were 82.6 males. For every 100 females age 18 and over, there were 80.5 males.

The median income for a household in the city was $20,800, and the median income for a family was $26,696. Males had a median income of $22,969 versus $16,898 for females. The per capita income for the city was $12,568. About 29.2% of families and 36.0% of the population were below the poverty line, including 50.3% of those under age 18 and 21.8% of those age 65 or over.